Blar i forfatter "Busund, Lill-Tove Rasmussen"
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The blood transcriptome prior to ovarian cancer diagnosis: A case-control study in the NOWAC postgenome cohort
Jareid, Mie Linnea; Snapkov, Igor; Holden, Marit; Busund, Lill-Tove Rasmussen; Lund, Eiliv; Nøst, Therese Haugdahl (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-27)Epithelial ovarian cancer (EOC) has a 5-year relative survival of 50%, partly because markers of early-stage disease are not available in current clinical diagnostics. The aim of the present study was to investigate whether EOC is associated with transcriptional profiles in blood collected up to 7 years before diagnosis. For this, we used RNA-stabilized whole blood, which contains circulating immune ... -
Global blood gene expression profiles following a breast cancer diagnosis - Clinical follow-up in the NOWAC post-genome cohort
Olsen, Karina Standahl; Holden, Marit; Thalabard, Jean-Christophe; Busund, Lill-Tove Rasmussen; Lund, Eiliv; Holden, Lars (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-08)<i>Objective</i> - This explorative study aimed to assess if there are any time-dependent blood gene expression changes during the first one to eight years after breast cancer diagnosis, which can be linked to the clinical outcome of the disease.<br><br> <i>Material and methods</i> - A random distribution of follow-up time from breast cancer diagnosis till blood sampling was obtained by a nested, ... -
Profiling of VEGFs and VEGFRs as prognostic factors in soft tissue sarcoma: VEGFR-3 is an independent predictor of poor prognosis
Smeland, E; Kilvær, Thomas Karsten; Valkov, Andrey Yurjevich; Sørbye, Sveinung Wergeland; Bremnes, Roy M.; Busund, Lill-Tove Rasmussen; Dønnem, Tom (Journal article; Tidsskriftartikkel; Peer reviewed, 2010) -
Rethinking the carcinogenesis of breast cancer: The theory of breast cancer as a child deficiency disease or a pseudo semi-allograft
Lund, Eiliv; Busund, Lill-Tove Rasmussen; Thalabard, Jean-Christophe (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-08-23)The theory of breast cancer as a <i>child deficiency disease</i> is an <i>inversion of the current paradigm</i>, which considers fullterm pregnancies to be a protective factor and uses nulliparous women as the reference group. Instead, the theory of breast cancer as a child deficiency disease says that women with the highest parity (about 20, which is the limit of human fertility) are those with ...